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Patients with uncontrolled seizure disorders, abnormal EEG findings of concern, active infection, significant cardiopulmonary disease, severe gastrointestinal or nutritional instability, marked immune dysfunction, known genetic or metabolic syndromes, or other serious coexisting conditions might not be appropriate candidates for the estimated treatment protocol

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Evaluation To assess fatigue, clinicians should initiate the evaluation by examining for modifiable causes of secondary fatigue