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This is why, at the beginning of the 20th century, when it was discovered that eating liver improved patients with pernicious anemia, they had to eat huge amounts to achieve a “pharmacological effect.” In these cases, we find an approximate absorption of, with luck, between 1-2% of the dose administered, but it is not uncommon for it to be even lower (0.5%) depending on the size of the dose, previous reserves, and other factors and individual conditions of each subject
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A structured approach to antioxidant-based therapies focuses on efficacy, safety, and synergistic combinations, providing a comprehensive strategy to protect the BBB, reduce neuronal damage, and effectively combat neurodegenerative diseases
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