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found that targeted interference with Nrf2 could effectively inhibit the expression of osteogenic related proteins and genes ALP, COL1, and Runx2, and further studies showed that curcumin could mediate the osteogenic differentiation of periodontal ligament cells by activating PI3K/AKT/Nrf2 signaling pathway (107)

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Meanwhile, Patricia Conklin and Rob Last were isolating ozone-sensitive Arabidopsis ethyl methanesulfonate (EMS) mutants