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4.2 CXCL10 and the inhibitors Recent studies report a Th1/IFN-γ immune response in both human and a mouse model of vitiligo that involves elevated CXCL9, 10, and 11 productions, among which CXCL10 participated in the targeted migration of T cells (72), and involved in the downregulation of keratinocyte glycoprotein non-metastatic melanoma protein B (GPNMB) (75)

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Vitamin B12 deficiency can manifest in several different types, each with distinct causes and characteristics: Dietary deficiency occurs when an individual does not consume enough foods containing vitamin B12, which is primarily found in animal products such as meat, fish, dairy, and eggs