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[67] Additionally, hCDR1 improved cognitive behavior and brain pathology in lupus mice [68] and downregulated the expression of the indoleamine 2, 3-dioxygenase (IDO) gene, which is increased in SLE patients
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Systemic copper homeostasis Copper is an essential trace nutrient in the human body, forming an integral part of various key metabolic enzymes like copper-zinc superoxide dismutase (SOD1), cytochrome c oxidase (CCO), and lysyl oxidase (LOX) (35)
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