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This is because dose reductions or interruptions can compromise cancer outcomes ( According to NCI clinical trial protocols, patients starting VEGF inhibitors should have blood pressure monitoring during the first cycle, followed by every 2–3 weeks while on therapy ( The ESC guidelines further stratify blood pressure management based on cancer prognosis ( The choice of antihypertensive medications in VEGF inhibitor-induced hypertension is critical (Figure 2)
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