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Additionally, the levels of proinflammatory cytokines, such as IL-6, IL-1, TNF-α, and inflammatory cytokine CD45 were remarkably decreased and the potential mechanism might through repression of the NF-κB signaling pathway, which showed that the SFN had protective effects in muscular inflammation of mdx mice through Nrf2-mediated repression of NF-κB signaling pathway [29-32]

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