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Furthermore, Eriodictyol has been shown to inhibit ferroptosis and improve cognitive deficits in APP/PS1 mice through activation of the Nrf2/HO-1 pathway (Li et al., 2022

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GSH is a powerful antioxidant that neutralizes ROS in a process catalyzed by one of the 4 selenium-dependant GPx proteins, thereby converting GSH to the oxidized state of glutathione disulfide (GSSG)