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Inositol — particularly myo-inositol — has been studied more seriously in insulin resistance and PCOS than in general weight loss, and it is not approved to treat any mental health condition despite the serotonin connection appearing in a lot of clinic copy

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Conversely, the de novo pathway and Preiss Handler pathway synthesize NAD + using nicotinic acid (NA) and tryptophan as substrates, respectively, albeit in smaller quantities