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Endoplasmic reticulum stress inhibition preserves mitochondrial function and cell survival during early onset of isoniazid-induced oxidative stress | bioRxiv
Moreover, iron is a critical cofactor for core bioenergetic processes such as mitochondrial respiration and oxygen transport and the Fe2+ required for ferroptosis (32)
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Interest in their combined use is based on overlapping mechanisms observed in preclinical models
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