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Loss of PRMT7 in the heart reduces symmetrical dimethylation of β-catenin, enhances Wnt-β-catenin signaling, and promotes myocardial hypertrophy
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REDEFINE 1 (Garvey et al., NEJM 2025) is the only Phase 3 trial of an amylin + incretin co-administered combination, pairing cagrilintide 2.4 mg with semaglutide 2.4 mg
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