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575 In SAMP8 mice, salidroside upregulates SLC7A11 and GPX4 protein expression through activating Nrf2/GPX4 axis, reduces iron deposition and ACSL4 protein expression, thereby inhibiting ferroptosis and Aβ accumulation, and alleviating cognitive impairment

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In total, the cycle from initial shedding to full recovery spans roughly nine to eighteen months