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The pharmaceutical composition of the present invention includes oxiracetam or a pharmaceutically acceptable salt thereof as an active ingredient, promotes muscle differentiation by increasing ATP activity required for myocytes or myoblasts to differentiate into myotubes, has a protective effect on myotubes atrophied by TNF-Ξ±, promotes grip strength improvement in a dexamethasone-induced animal model and an aging animal model, induces muscle loss inhibition and recovery mass of the tibialis anterior muscle, and promotes muscle regeneration or grip strengthening and inhibits muscular atrophy or muscle loss by increasing the recovery of lean body mass and the gastrocnemius muscle
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