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Here, we show that in vivo secretion of the proinflammatory mediators IL-6 and IFNγ in response to CpG was significantly decreased in the plasma of CpG-challenged mice after treatment with ENDO12 (Fig

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Of particular interest, NRF2 activation may also reduce phosphorylated TAU protein via the autophagy-lysosome pathway through the induction of the autophagy adaptor protein NDP52 [241]