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Abbreviations BALF bronchoalveolar lavage fluid CCL chemokine (C-C motif) ligand EGF epidermal growth factor ESAT-6 early secreted antigenic target 6kDa protein GM-CSF granulocyte-macrophage colony-stimulating factor GvHD graft-versus-host disease HBV hepatitis B virus HSCT haematopoietic stem cell transplantation IFN-γ interferon gamma IL interleukin ILC2 innate lymphoid cells type 2 iNOS inducible nitric oxide synthase LPS lipopolysaccharide M-CSF macrophage colony-stimulating factor MHC major histocompatibility complex mTOR mammalian target of rapamycin NFκB nuclear factor kappa-B NLRP3 NOD-like receptor family, pyrin domain containing 3 NO nitric oxide PD-L1 programmed cell death ligand 1 PGE2 prostaglandin E2 RA rheumatoid arthritis RANKL receptor activator of nuclear factor kappa B ligand RNS reactive nitrogen species ROS reactive oxygen species SLE systemic lupus erythematosus TAMs tumor-associated macrophages TGF transforming growth factor TIM-3 T cell immunoglobulin and mucin-domain containing 3 TLR Toll-like receptor TME tumor microenvironment TNF tumor necrosis factor TRAF6 tumour-necrosis factor receptor associated factor 6 VEGF vascular endothelial growth factor Data Availability The manuscript does not contain any original data