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In contrast, oral administration at standard therapeutic doses (500–1000 mg/day) is well tolerated in humans, with adverse effects being uncommon and usually mild [9]

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In contrast, the antagonist-bound heteromeric GluK2/GluK5 and GluK2-Neto2 assemblies adopted the canonical two-fold symmetrical dimer-of-dimers arrangement of LBDs (He et al., 2021