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Results FA excess or B 12 deficiency delays the generation and/or migration of cortical upper layer projections neurons To test the effects of gestational maternal folate/B 12 intake on the offspring, we created five nutritional groups of C57BL/6NJ dams that were fed amino acid defined rodent chow (Dyets Inc., Bethlehem, PA): (1) control, (2) high FA, (3) low B 12 , (4) high FA/low B 12 , and (5) high 5-FTHF

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This reduces overeating and helps patients maintain caloric deficits more comfortably