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Frontiers | Advances in drug delivery systems for the management of gout and hyperuricemia

S.AzziJ.MacLaurinJ

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394 Collectively, these findings underscore that while endogenous stimuli-responsive microdevices carry significant therapeutic potential, their clinical translation depends on a deeper mechanistic understanding of physiological variability, rigorous long-term biocompatibility evaluation, and comprehensive in vivo validation to ensure consistent and safe performance across diverse patient populations

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