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Head-to-Head Research Comparisons in 3D Skin Models In 3D reconstructed human epidermis (EpiDerm, MatTek), UV-B challenge (100 mJ/cm²), 24h post-irradiation assessment: MT-2 pre-treatment (10nM, 72h): melanin content +68% (Fontana-Masson), CPD+ cells −38% (IHC), TEWL +28% versus +48% in UV+vehicle — indicating improved barrier function through pigment-mediated UV attenuation
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[DOI] [PMC free article] [PubMed] [Google Scholar] 152.Young A.B., Snyder S.H