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The computed energy barrier for Cu(II)-catalyzed methionine oxidation is 14.3 kcal/mol —significantly lower than for Zn²⁺ (19.6 kcal/mol) or Fe³⁺ (16.9 kcal/mol), making copper the most efficient catalyst among common metal ions

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10.2174/1381612826666200523180301 51 PereiroX.RuzafaN.UrcolaJ