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Nevertheless, even when samples are treated with thiol-masking agents to prevent thiols artificial oxidation, in most cases unreliable compounds are used and/or they are not added at the proper time and the bias is still present

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Similarly, research exploring cellular clearance of senescent cells often pairs bioregulators with selective senolytics like FoxO4-DRI, which induces apoptosis in senescent cells by disrupting the FOXO4-p53 interaction

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