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Keywords: Brain aging, Cognitive decline, GHK-Cu, Intranasal delivery, Aging mouse model, Neuropathology Introduction The ability to respond to and recover from a physically stressful event is defined as physical resilience [1]

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organ protective activity: protection of hepatic and pancreatic lesions, protection of endothelial cells, prevention of adhesion formation, prevention and treatment of myocardial infarction and brain stroke, protective effect in immune system