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Key research findings: A 2024 clinical trial published in Archives of Dermatological Research found PDRN polynucleotide gel significantly improved pattern hair loss tolerability and satisfaction scores (PubMed 38842633) PDRN promotes dermal papilla cell proliferation through A2A receptor-mediated VEGF upregulation Anti-inflammatory action reduces TNF-α and IL-6 levels, protecting follicles from chronic scalp inflammation Used in: Hairgenetix Meso-Infusion System (PDRN-enriched serum vials) How Do These Treatments Compare