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Systematic reviews across orthopaedic indications now show clinically relevant advantages for PRP over alternatives: Knee osteoarthritis: Multiple meta-analyses (2024–2025) report superior pain and function outcomes vs hyaluronic acid and better results than corticosteroid/placebo over short- to mid-term follow-up

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The most important group for weight loss is GLP-1 receptor agonists such as semaglutide and liraglutide