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After myelin damage, OPCs are recruited to the demyelinated lesion core and differentiated into mature OLs to generate new myelin sheaths, a repair process referred to as remyelination [5]

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Amplified fragments were purified with AMPure XP Beads (Beckmann Coulter Genomics), combined and analyzed by “2 × 300 bp paired-end” sequencing using an Illumina MiSeq device