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These were the endothelium damaging agents, i.e., alcohol [32] or lithium [31], bile duct occlusion (acute pancreatitis) [29], organs and vessels compression (intra-abdominal hypertension) [31]

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In aging research, the compound provides a unique approach to investigating theories of metabolic decline, as NNMT expression increases with age in many tissues, potentially contributing to the NAD+ decline associated with aging processes