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doi: 10.1621/nrs.07003

Serums and Essence

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Genesis of Oxidative Stress in Diabetes Oxidative stress in diabetes arises from a complex interplay of various factors, including the accumulation of glycolysis intermediates, activation of the polyol pathway, formation of AGEs, activation of Protein Kinase C (PKC), and activation of the hexosamine pathway (Figure 1) [13]