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Figure 4 4.1 Small-molecule antioxidants and ER stress inhibitors Therapeutic strategies targeting oxidative stress and endoplasmic reticulum stress (ERS) have attracted increasing attention due to their central involvement in secondary neuronal injury after TBI (Li et al., 2023)

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For example, monomorphic and metamorphic proteins, although generally stable, can still contain shorter flexible and dynamic regions, typically in extruding loops or in termini