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20, 55 As p53 abnormalities are associated with poor prognosis in MM, 2, 49 the ability of BSO+L-PAM to induce cell death by circumventing p53 loss-of-function may provide a viable therapeutic option for patients with del17p13 MM

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For standard insulin syringes with fixed needles, dead space is minimal (around 0.005-0.01 mL)