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A first-in-human Phase I trial found that rectal administration of PL 14736 in healthy male volunteers was safe and well tolerated, with favorable pharmacokinetics that supported moving into patient trials (Veljaca et al., published in Gut , 2003)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 134.Schröck A, Thierauf-Emberger A, Schürch S, Weinmann W
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