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SC Tmax: typically 1–4 hours depending on peptide molecular weight IM Tmax: typically 30 minutes to 2 hours SC produces flatter, more sustained plasma curves IM produces sharper peaks with faster clearance Peptide molecular weight affects diffusion rate through both tissues Reconstitution vehicle (bacteriostatic water vs saline) can influence local absorption Which Peptides Use Which Route Research literature establishes clear route preferences for major peptide categories

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