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Introduction Glutathione (GSH), or l-γ-glutamyl-l-cysteinyl-glycine, is a tripeptide present in mammalian cells at surprisingly high levels (1–10 mM) and particularly concentrated in the liver [1,2]

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Supplementation of RES in mouse models has demonstrated slowed fat regeneration in muscle, enhanced AMPK activity, and increased mitochondrial biogenesis