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The disease in dogs is characterized by fever, enlarged lymph nodes, ocular discharge, and edema of the eyelids, followed by vomiting, then diarrhea and later severe dysentery, and death in untreated cases

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Furthermore, exposure of paclitaxel to cultures derived from human DRG neurons elicits an increase in the expression of Nav1.7, but not that of Nav1.8 (Chang et al., 2018)