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[11] [12] Magnesium pidolate, the magnesium salt of pyroglutamic acid, is found in some mineral supplements

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Interestingly, in sickle cell anemia, erythrocytes that are constantly subjected to oxidative stress due to rapid autoxidation of sickle hemoglobin (66) have a significant increase in the V max and a decrease in K m for Na + -dependent, secondary active transport of glutamine and the increased rate of entry of glutamine results in accumulation of glutamate (67)