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Larger groups create greater steric strain, giving greater instability to the chair conformation when in the axial position

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Global Peptide Therapy Market Statistics Global peptide therapy market value (2025): USD 84.2 billion — CAGR 14.74% (2026–2031) → USD 196.5 billion by 2031 Global peptide therapy volume (2025): 20.2 billion dosage units — volume CAGR 21.24% → 65.5 billion units by 2031