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CRISPR/Cas9-mediated gene editing using LNPs has shown feasibility and efficacy, particularly in liver-related disorders [335]

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It is noteworthy that pre-treatment with AGE significantly improves short-term recognition memory in rats with Aβ-induced neurotoxicity along with the reduction of the activation of microglia in the cerebral cortex and hippocampus via the decrease in the immunohistological staining of integrin aM or CD11b protein