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Typical Onset Timelines From Clinical Trials In the clinical trial data we have so far, cagrilintide appetite suppression generally follows a dose-dependent pattern: First 1–2 days: Some participants reported mild appetite reduction, likely related to the initial pharmacological effect on gastric emptying and early amylin receptor activation

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Crews FT, Criswell HE, Morrow AL, Breese GR (1996)