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The inflammation is a critical component of the progression and maintenance of the pathophysiology of neuropathic pain [6], in which the Wallerian degeneration of axons and myelin sheaths occurring after nerve injury is accompanied by the secretion of inflammatory cytokines, chemokines, and oxidative mediators, the recruitment of macrophages and other immune cells, and the activation of resident astrocytes and microglial cells [7]
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For clinicians and people who like to read studies BMC Clin Pharmacol , 2010 (full citation in References below)
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