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Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) that irreversibly inhibits cyclooxygenase (COX) enzymes, mainly COX-1 and COX-2. It does this by acetylating a serine residue at the active site of the enzyme
2007;66(suppl 3):i70–iii76
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For instance, Jonny et al (47) conducted a systematic review on the therapeutic potential of tolDCs in autoimmune diseases, including systemic lupus erythematosus, demonstrating that the induction of tolDCs in vitro can effectively modulate T-cell responses and promote antigen-specific immune tolerance
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