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Following an evaluation of TCS by the Biocidal Products Committee of the European Chemicals Agency (ECHA), the European Commission (EC) decided in 2016 that TCS is not approved for use in human hygiene biocidal products [49,50], but maintained its legality as a preservative in selective cosmetics and mouthwashes in concentrations up to 0.3% and 0.2%, respectively [18,51]