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negundo contains triterpenes, diterpenes, sesquiterpenes, lignan, favonoids, favones, glycosides, iridoid glycosides and stilbene derivative ( Hydroalcoholic extract of plumbago zeylanica leaves With the bioactive components of L-dopa, plumbagin, droseron, chitranone, triterpinoid, and anthraquinone, the hydroalcoholic extract of PZL effectively reduced haloperidol-induced elevation of catalepsy in Wistar rats ( Therapeutic effects of aqueous extract of individual herbs on the APDs-induced EPS-like behaviors and neurobiological changes ( Table 5 ) Table 5 Therapeutic effects of aqueous extracts of herbs on EPS-like behaviors and the underlying neurobiological changes
