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Crucially, the ROS generated during GSH degradation by CHAC1 may also cause further TP53 mutations, creating a vicious self-reinforcing cycle: CHAC1 activity promotes the very TP53 mutations that allow the tumor to exploit CHAC1′s harmful effect for growth

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Limonen ist ein Naturstoff, der in Fenchel, Sellerie, Kirschen, Soja- und Weizenprodukten vorkommt