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Accordingly [12,13,14,15,16,20,22,23,24], superior sagittal sinus pressure of −24 to −27 mmHg, portal pressure of 3–5 mmHg, similar to that of the inferior vena cava although with values at least 1 mmHg higher in the portal vein, and abdominal aorta blood pressure values of 100–120 mmHg at the level of the bifurcation were considered as normal in healthy rats
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25 IC/BPS patients with widespread pain had more severe urologic symptoms, worse psychosocial symptoms and functioning, poorer QoL, and a worsening symptom trajectory over time