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We propose that microglial-mediated pruning of excitatory synapses in the prefrontal cortex (PFC) reduces the synaptic gain required to signal new sensory data, leading to reduced sensory precision 42,43,44

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78% were White,16% were Asian, 2.9% were Hispanic or Latino, 2.1% were Black or African American, and 80 mL/min following concomitant administration of ibuprofen (OAT3 inhibitor) 400 mg four times a day