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This result verifies the penetration of the CRISPR/Cas9 magnetoplexes into the nucleus and dissociation of DNA from the magnetoplexes into the nucleus

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(2) Exogenous administration of 7,8-DHF could reach the brain through the BBB and produce the effect of simulating BDNF, which made up for the poor pharmacokinetics of exogenous supply of BDNF