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The presence of predicted conserved motifs and domains, chromosomal and subcellular localization and their sequence homology with other identified GSTs from other organisms provided insight into their structure and putative functions

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Accordingly, mechanistically credible interpretation across studies requires consistent reporting of curcumin identity and composition, formulation class, dose (mg/kg), route, dosing duration and timing relative to injury induction, feeding matrix (including lipid content for oral studies), and—where feasible—evidence of systemic or tissue exposure (e.g., plasma/tissue detection or pharmacokinetic parameters)