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Additional endothelial biology research demonstrated that BPC-157 promoted proliferation, migration, and tube formation in human umbilical vein endothelial cells in vitro, with authors linking these responses to ERK1/2 signaling pathway activation [7]

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Pleiotropic beneficial effects occurred in the lesions in the brain, heart, lung, liver, kidney, and gastrointestinal tract, as well as in the reversal of severe multiorgan and vessel failure, reversal of occlusion/occlusion-like syndrome as a whole [4,10], and reversal of advanced Virchow triad circumstances