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This regulatory relationship highlights CHAC1’s potential role in modulating oncogenic signaling pathways, making it a candidate for targeted therapy in diseases like uveal melanoma where PI3K/AKT signaling is dysregulated ( 3.4 DJ-1 DJ-1 is a protein encoded by the PARK7 gene, which is implicated in autosomal recessive early-onset Parkinson’s disease (PD)

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doi: 10.1080/10715760701286159