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Of the three haplotypes, the upstream genetic alterations that were in linkage disequilibrium with the Leu allele were also found to have the lowest level of activity in a transcription reporter gene assay, causing a 25% suppression in promoter activity (152)
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Pregnant or breastfeeding individuals: there is no adequate safety data for GHK-Cu in pregnancy or lactation, so the conservative choice is to avoid it absent medical advice
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