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The study confirmed that the high-polarity metabolites of Gastrodia elata (T1) exerted the best therapeutic effect through anti-oxidation, anti-inflammation and repair of energy and amino acid metabolism disorders, in which water-soluble phenols and polysaccharides were the key active metabolites, providing a scientific basis at the metabolomic level for the application of Gastrodia elata in the treatment of gastritis (Xu et al., 2020)